Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Internal Carotid Artery Stenosis Grade (according to NASCET criteria) assessed by Non-contrast Magnetic Resonance Angiography and Carotid Doppler ultrasonography.
研究概览
简要总结
This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among patients with ischemic cerebrovascular stroke or transient ischemic attack. A total of 200 adult patients presenting to Sohag University Hospital will undergo both imaging modalities. The study will assess the agreement between NC-MRA and carotid Doppler in detecting and grading carotid artery stenosis according to the NASCET criteria, with the goal of evaluating the clinical utility of each technique and optimizing imaging strategies for the assessment of cerebrovascular stroke.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years or older.
- •Clinically diagnosed ischemic stroke or transient ischemic attack (TIA).
- •Imaging performed within 7-14 days of symptom onset.
- •Hemodynamically stable and suitable for magnetic resonance imaging (MRI).
- •Able and willing to provide written informed consent.
排除标准
- •Hemorrhagic stroke.
- •Previous carotid artery stenting.
- •Contraindications to MRI, including:
- •Non-MRI-compatible pacemakers or other MRI-incompatible implants.
- •Cochlear implants.
- •MRI-incompatible metallic orthopedic implants.
- •Severe claustrophobia.
研究组 & 干预措施
Patients with Ischemic Stroke or Transient Ischemic Attack
Adult patients (≥18 years) with clinically diagnosed ischemic stroke or transient ischemic attack who undergo both carotid Doppler ultrasonography and non-contrast magnetic resonance angiography for evaluation of carotid artery disease. The findings of the two imaging modalities will be compared for the assessment of carotid artery stenosis and atherosclerotic plaque characteristics.
结局指标
主要结局
Internal Carotid Artery Stenosis Grade (according to NASCET criteria) assessed by Non-contrast Magnetic Resonance Angiography and Carotid Doppler ultrasonography.
时间窗: At the baseline imaging visit (within 7-14 days of symptom onset).
Internal carotid artery stenosis grade in patients with ischemic stroke or transient ischemic attack determined according to the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria using non-contrast magnetic resonance angiography and carotid Doppler ultrasonography. The stenosis grades obtained by the two imaging modalities will be compared.
次要结局
未报告次要终点
研究者
Mohamed Saad Gad
Radiology Resident
Sohag University