Crocin in acute kidney injury
Phase 3
Recruiting
- Conditions
- Contrast induced nephropathy.Nephropathy induced by other drugs, medicaments and biological substancesN14.1
- Registration Number
- IRCT20200202046335N1
- Lead Sponsor
- Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Undergoing coronary or peripheral angiography with or without intervention
Cr > 1.2 mg/dL and 30 Systolic pressure of greater than 90 mm Hg
No contraindications to hydration or contrast agent
Exclusion Criteria
History of hypersensitivity to saffron
End-stage renal disease on dialysis
Acute renal failure
Pregnancy or lactation
Emergent coronary angiography, ST elevation myocardial infarction (STEMI), or cardiogenic shock
Patient receiving N-acetylcysteine or sodium bicarbonate
Platelets less than or equal to 100,000/mm3
Left Ventricular ejection fraction less than 30
History of Kidney transplant
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BUN & Creatinin. Timepoint: Before intervention and 24 and 72 hrs after that. Method of measurement: blood urine nitrogen and creatinine lab test.;(NGAL)Neutrophilic Gelatinase Associated Lipocaline. Timepoint: before and 8 hrs after angiography. Method of measurement: urine sample collection in urine sample containers.
- Secondary Outcome Measures
Name Time Method