Chilli versus aspirin: effect on platelet aggregation and vascular function.

Not Applicable

Recruiting

• Conditions: Platelet hyperactivation; Blood pressure; Diet and Nutrition - Other diet and nutrition disorders; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12611000576921
• Lead Sponsor: niversity of Tasmania

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-06-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

No history of renal disease
No diabetes, liver disease or other heart conditions
Not currently taking aspirin or aspirin-like medication, NSAIDS, steroids or omega-3 fatty acid supplements

Exclusion Criteria

Have gluten intolerance

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Platelet aggregation - measured in vitro by platelet aggregometry[For 2hr tests - fasting (immediately prior to the meal) and then at 60 minutes and 120 minutes <br>For 1 hr tests - fasting (immediately prior to the meal) and then at 60 minutes.]

Secondary Outcome Measures

Name	Time	Method
Brachial and central blood pressure measured with pulse wave analysis (PWA) technique[For 2 hr tests - fasting (immediately prior to the meal) and then every fifteen minutes for 120 minutes.<br>For 1 hr tests - fasting (immediately prior to the meal) and then every fifteen minutes for 60 minutes.];Plasma 6-keto prostaglandin F1a measured by ELISA method[For 2 hr tests - fasting (immediately prior to the meal) and then at 20, 40, 60, 90 and 120 minutes.<br>For 1 hr tests - fasting (immediately prior to the meal) and then at 20, 40, 60 minutes.];Plasma glucose and insulin[For 2 hr tests - fasting (immediately prior to the meal) and then at 5, 10, 20, 40, 60, 90 and 120 minutes.<br>For 1 hr tests - fasting (immediately prior to the meal) and then at 5, 10, 20, 40, 60 minutes.]