Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis

Completed

• Conditions: Uremia; End Stage Renal Disease on Dialysis

• Registration Number: NCT07086430
• Lead Sponsor: RenJi Hospital

Brief Summary

It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-21
• Primary Completion: 2023-07-11
• Status Verified: 2025-04
• Study Completion: 2025-05-01
• Study First Submitted: 2025-07-14
• Study First Submitted QC: 2025-07-24
• Last Update Submitted: 2025-07-24
• Study First Posted: 2025-07-25
• Last Update Posted: 2025-07-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 358

Inclusion Criteria

• The study included peritoneal dialysis patients follow up in our center who had an abdominal CT scan within 2 weeks before PD catheter incubation.

Exclusion Criteria

• Those with acute inflammation according to clinical signs, lab results or abdominal CT scan were excluded from the cohort.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the association between peritoneal membrane solute transfer rate and abdominal visceral adipose tissue density measured on CT	from the baseline, 4 weeks before PD catheter insert surgery until patients quit PD or follow up up to 48 months