Double-Blind Comparison of Intravenous Cyclophosphamide and Intrathecal Methotrexate Plus Dexamethasone in Neuropsychiatric Lupus Erythematosus Patients
Phase 1
Recruiting
- Conditions
- europsychiatric Lupus Erythematosus
- Registration Number
- ITMCTR1900002487
- Lead Sponsor
- anjing Integrated Traditional Chinese and Western Medicine Hospital Affiliated with Nanjing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
The patients were diagnosed as NPSLE, younger than 65 years old, with normal blood routine and liver and kidney function.
Exclusion Criteria
Patients with leukopenia; cardiopulmonary insufficiency; patients with central nervous system infection; unable to accept lumbar puncture therapy; there are also 1) patients who are participating in other clinical trials; 2) Researchers believe that other reasons are not suitable for clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cerebrospinal fluid;
- Secondary Outcome Measures
Name Time Method Symptom relief time;Incidence of toxic and side effects;