Correlation of Interleukin with viruses in gum disease.

Not Applicable

Completed

• Conditions: Health Condition 1: null- Chronic and Aggressive patients

• Registration Number: CTRI/2018/08/015221
• Lead Sponsor: DR SHIVAPRASAD BM

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-04-30
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

1 Systematically healthy patients and showing the absence of clinical manifestations of periodontal disease.

2 Chronic periodontitis patients having at least 20 natural teeth and minimum of 6 teeth with periodontal pockets >= 5mm and clinical attachment level >= 3-4mm.

3 All the patients should be systematically healthy and should not have received periodontal treatment for last 6 months prior to the clinical examination and sampling.

4 Generalised aggressive periodontitis patients with clinical attachment level >= 5mm affecting atleast 3 teeth other than first molars and incisors and moderate to severe bone loss as assessed by radiographs

Exclusion Criteria

1 Smokers

2 Systemic diseases like diabetes mellitus, heart diseases, rheumatoid arthritis, hepatitis and other systemic diseases that can alter the course of periodontal disease.

3 Diseases of oral hard and soft tissue except caries and periodontitis.

4 Subjects on any medication taken within last 6 months which may alter the periodontal status.

5 Pregnant and lactating mothers.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evels of Interleukin 28A mRNA expression in gingival crevicular fluid and gingival tissues of chronic and aggressive periodontitis patientsTimepoint: Levels of Interleukin 28A mRNA expression in gingival crevicular fluid and gingival tissues of chronic and aggressive periodontitis patients will be assessed at baseline immediately after collection of samples

Secondary Outcome Measures

Name	Time	Method
Gingival index score clinical attachment level and probing pocket depth of chronic and aggressive periodontitis patientsTimepoint: Gingival index score clinical attachment level and probing pocket depth of chronic and aggressive periodontitis patients will be assessed at baseline at the time of sample collection