NCT00205127已完成不适用
Comparison of Cardiac Perfusion by O15-water and F17-fluoromethane PET
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- -- implement myocardial perfusion quantification for O15-labeled water at rest and with pharmacologic stress,
研究概览
简要总结
In this study we are looking at the blood flow to the heart using two different chemical tags or tracers that give off a low level of radiation. The tracers used in this study are called O15-water and F17-fluoromethane. These tracers mix with the blood and will move through the body. The researchers will use positron emission tomography (PET scans)to track the tracers as they moe through the heart and chest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •1. Age 18 to 40 years old
- •Willing to provide written informed consent
排除标准
- •1. A history of CAD
- •A history of active bronchospasm or asthma on theophylline bronchodilators
- •A history of any cardiac risk factors including: HTN, Diabetes, Hyperlipidemia, Smoking, and premature CAD in immediate family member
- •A history of liver disease or other significant disease
- •Females who are pregnant or lactating
结局指标
主要结局
-- implement myocardial perfusion quantification for O15-labeled water at rest and with pharmacologic stress,
时间窗: assess at time of PET scan
-- determine the biodistribution of fluoromethane in the thorax to see if it is usable for a cardiac perfusion tracer,
时间窗: assess at time of PET Scan
次要结局
- --develop initial methods for quantification of myocardial perfusion if applicable for labeled fluoromethane.(assess at time of PET scan)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Comparative study of the influence of blood flow, oxygenation and hemodynamics generated during the use of extracorporeal circulation machineheart failure, coronary insufficiency, myocardial infarctionC14.280.647.187.150RBR-48x3xvInstituto Nacional de Cardiologia
尚未招募
不适用
Comparison of physiological response and recovery during lying straight and reverse position of kidney stone operation with dexmedetomidine (medicine) infusion.CTRI/2019/09/021463Md Sanaul Islam70
已完成
不适用
Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF)Coronary Heart DiseaseNCT02280941Ottawa Heart Institute Research Corporation66
尚未招募
不适用
Comparison of blood pressure,heart rate and other parameters in old and the very old for hip replacement surgery.CTRI/2017/04/008301okmanya Tilak Municipal General HospitalMumbai90
已完成
不适用
Evaluation of cardiac perfusion, structure and function in chronic liver and kidney diseaseCardiovascular disease as result of chronic liver and chronic kidney diseaseCirculatory SystemISRCTN16005265niversity of Nottingham (UK)30