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临床试验/ISRCTN16005265
ISRCTN16005265已完成未知

Evaluation of cardiac perfusion, structure and function in chronic liver and kidney disease: A cross-sectional observational study

niversity of Nottingham (UK)0 个研究点目标入组 30 人开始时间: 2014年8月19日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • 1. Age above 18 and below 65 years
  • 2. Able to give informed consent
  • And either:
  • 3. CKD Stage 3b (eGFR> 30 and <44 ml/min) or
  • 4. Compensated Cirrhotic Liver Disease proven radiologically or on biopsy

排除标准

  • 1. Known cardiac disease- previous myocardial infarction, angina, arrhythmias including AF, cardiac surgery, myocarditis, pericarditis or other non-specified cardiac conditions
  • 2. Taking beta blockers, calcium channel blockers or other rate/rhythm controlling medication
  • 3. Unstable CKD ? AKI Stage 1 or more or other unplanned hospital admission relating to their kidney disease in the last 30 days
  • 4. Unstable CLD ? Clinical decompensation or other unplanned hospital admission relating to their liver disease in the last 30 days
  • 5. For liver patients ? previous Transjugular Portosystemic Shunt (TIPSS) insertion
  • 6. Pregnant, breastfeeding or intending pregnancy
  • 7. Unable to give consent or understand written information
  • 8. Contraindications to MRI ? pacemaker, metallic fragments or implants, known claustrophobia
  • 9. Inability to sustain 20 minutes of light exercise
  • 10. Diabetes

研究者

发起方
niversity of Nottingham (UK)

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