ISRCTN16005265
Completed
N/A
Evaluation of cardiac perfusion, structure and function in chronic liver and kidney disease: A cross-sectional observational study
niversity of Nottingham (UK)0 sites30 target enrollmentAugust 19, 2014
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Cardiovascular disease as result of chronic liver and chronic kidney disease
- Sponsor
- niversity of Nottingham (UK)
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age above 18 and below 65 years
- •2\. Able to give informed consent
- •And either:
- •3\. CKD Stage 3b (eGFR\> 30 and \<44 ml/min) or
- •4\. Compensated Cirrhotic Liver Disease proven radiologically or on biopsy
Exclusion Criteria
- •1\. Known cardiac disease\- previous myocardial infarction, angina, arrhythmias including AF, cardiac surgery, myocarditis, pericarditis or other non\-specified cardiac conditions
- •2\. Taking beta blockers, calcium channel blockers or other rate/rhythm controlling medication
- •3\. Unstable CKD ? AKI Stage 1 or more or other unplanned hospital admission relating to their kidney disease in the last 30 days
- •4\. Unstable CLD ? Clinical decompensation or other unplanned hospital admission relating to their liver disease in the last 30 days
- •5\. For liver patients ? previous Transjugular Portosystemic Shunt (TIPSS) insertion
- •6\. Pregnant, breastfeeding or intending pregnancy
- •7\. Unable to give consent or understand written information
- •8\. Contraindications to MRI ? pacemaker, metallic fragments or implants, known claustrophobia
- •9\. Inability to sustain 20 minutes of light exercise
- •10\. Diabetes
Outcomes
Primary Outcomes
Not specified
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