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Clinical Trials/NCT05113082
NCT05113082
Completed
N/A

A Multicentric Observational Retrospective Study on Patients With Short Bowel Syndrome and Chronic Intestinal Failure That Underwent Intestinal Transplantation in Brazil

Takeda1 site in 1 country7 target enrollmentMay 21, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Short Bowel Syndrome (SBS)
Sponsor
Takeda
Enrollment
7
Locations
1
Primary Endpoint
Elapsed Time From the Date of Underlying Condition Diagnosis to the Date of SBS-IF Diagnosis
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The main aim of this study is to capture management and treatment outcome data in participants with short bowel syndrome and chronic intestinal failure (SBS-IF) that underwent intestinal transplantation in Brazil.

This study is about collecting data available in the participant's medical record and will also describe the demographic and clinical characteristics of these participants. No medication will be provided to participants in this study.

Clinical data will be collected from a period up to 10 years before the day of the intestinal transplantation. No clinic visits will be required as part of participation in this study.

Registry
clinicaltrials.gov
Start Date
May 21, 2022
End Date
October 15, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Takeda
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Elapsed Time From the Date of Underlying Condition Diagnosis to the Date of SBS-IF Diagnosis

Time Frame: From start of the study up to end of observation period (up to 10 months)

Elapsed time from the date of underlying condition diagnosis to the date of SBS-IF diagnosis, according to the information described in the medical records will be presented using a Kaplan-Meier curve. Elapsed time is defined as the amount of time that passes from the beginning of an event to its end.

Elapsed Time From the Date of Intestinal Transplant Indication to the Date of Intestinal Transplant Procedure

Time Frame: From start of the study up to end of observation period (up to 10 months)

Elapsed time from the date of intestinal transplant indication to the date of intestinal transplant procedure, according to the information described in the medical records will be presented using a Kaplan-Meier curve. Elapsed time is defined as the amount of time that passes from the beginning of an event to its end.

Elapsed Time From the Date of SBS-IF Diagnosis to the Date of Intestinal Transplant Procedure Indication

Time Frame: From start of the study up to end of observation period (up to 10 months)

Elapsed time from the date of SBS-IF diagnosis to the date of intestinal transplant procedure indication, according to the information described in the medical records will be presented using a Kaplan-Meier curve. Elapsed time is defined as the amount of time that passes from the beginning of an event to its end.

Secondary Outcomes

  • Number of Participants Based on Type of Parenteral Nutrition and Fluid (IV) Support From Site Admission Until Intestinal Transplantation(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants With Hospitalization Related to SBS-IF Disease Since Site Admission Until Intestinal Transplantation(From start of the study up to end of observation period (up to 10 months))
  • Length of Hospitalization Related to SBS-IF Disease(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants Based on Reason/Indication for Hospitalization in SBS-IF Participants(From start of the study up to end of observation period (up to 10 months))
  • Percentage of Participants With Each Disease Leading to SBS-IF(From start of the study up to end of observation period (up to 10 months))
  • Volume of Parenteral Nutrition and Fluid (Intravenous [IV]) Support From Site Admission Until Intestinal Transplantation During Intestinal Transplantation(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants Based on Reasons for Intestinal Transplant Indication(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants Based on Anatomy Site(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants With Parenteral Nutrition and Fluid (IV) Support From Site Admission Until Intestinal Transplantation(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants Based on Each Type of Intestinal Transplant Performed(From start of the study up to end of observation period (up to 10 months))
  • Number of Participants With Surgery Performed in SBS-IF Participants(From start of the study up to end of observation period (up to 10 months))
  • Length of the Remaining Bowel(From start of the study up to end of observation period (up to 10 months))

Study Sites (1)

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