Comparison of different dosage of oxytocin for initiating uterine contraction during cesarean delivery: A randomized, double-blind, controlled, non-inferiority trial
Phase 4
- Conditions
- Adequate uterine contraction at 3 minutesUterine contraction (verbal numerical scale 0 ᆞ)Additional doses of uterotonic drugsAdditional obstetrics proceduresNausea/VomitingFlushingTachycesarean deliveryoxytocininitiating uterine contraction
- Registration Number
- TCTR20190415001
- Lead Sponsor
- Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
ASA physical status class II
singleton pregnancy
gestational age 37-42 weeks
patients were planned for cesarean delivery
patients were planned for spinal anesthesia
Exclusion Criteria
failed or inadequate spinal anesthesia
high risk of uterine atony (macrosomia, twins, chorioamnionitis, polyhydramnios, myoma uteri)
previous uterus surgery (except cesarean section)
high risk of postpartum hemorrhage (placenta previa, history of previous postpatum hemorrhage, coagulopathy, thrombocytopenia, PIH)
contraindication of spinal anesthesia
allergy to oxytocin
refuse to be volunteer
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method adequate uterine contraction at 3 minutes after oxytocin administration evaluated by surgeon
- Secondary Outcome Measures
Name Time Method effectiveness administration time - 15 minutes after administration additional doses of uterotonic drugs, additional obstetrics procedures, uterine contraction (verbal ,adverse effects administration time - 15 minutes after administration told by subjects, evaluated by outcome assessor