Comparison of oxytocin low-rate infusion versus oxytocin bolus for initiating uterine contraction during cesarean delivery: A randomized, controlled, non-inferiority trial
Phase 4
Recruiting
- Conditions
- Pregnancy undergoing for elective Cesarean delivery under spinal anesthesiaoxytocin, oxytocin bolus, oxytocin infusion, uterine atonypostpartum hemorrhage, Cesarean section, Cesarean delivery
- Registration Number
- TCTR20221113003
- Lead Sponsor
- Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
Pregnancy aged 18-40 years old, GA 37-42 weeks, ASA ll, singleton, scheduled undergoing elective Cesarean delivery under spinal anesthesia
Exclusion Criteria
Previous uterine surgery other than cesarean section, high risk of uterine atony (macrosomia, chorioamnionitis, polyhydramnios, uterine mass), high risk of postpartum hemorrhage (placenta previa or other placenta disorders, history of postpartum hemorrhage, coagulopathy, thrombocytopenia, pre-eclampsia)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adequate uterine contraction at 3 minutes after fetal delivery percentage
- Secondary Outcome Measures
Name Time Method terine tone at 3 minutes after fetal delivery percentage,Additional uterotonic agents after fetal delivery percentage,Estimate blood loss more than 500 ml after fetal delivery percentage,Mild adverse effects (nausea/vomiting, flushing, tachycardia) after fetal delivery until end of operation percentage,Severe adverse effects (hypotension, chest pain, EKG change) after fetal delivery until end of operation percentage