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se of oxytocin at different rates for contraction of uterus during planned caesarean delivery

Phase 4
Completed
Conditions
Health Condition 1: null- Full term pregnant patients undergoing elective caesarean section
Registration Number
CTRI/2017/11/010462
Lead Sponsor
niversity College of Medical Sciences and GTB Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

Healthy females with 37 weeks gestation or more,

Age between 18 and 40 years,

Uncomplicated singleton pregnancy,

Patients undergoing elective caesarean section under spinal anaesthesia

Exclusion Criteria

Patients in active labour;

Ruptured membranes;

Known drug allergy to oxytocin;

Maternal complications e.g. pre-eclampsia, diabetes mellitus, cardiovascular disease, cerebrovascular disease, bronchial asthma;

Known risk factors for postpartum haemorrhage e.g. Multiple gestation, abnormal placentation, uterine fibroid, macrosomia, hydramnios, history of postpartum haemorrhage or uterine atony;

Patients with absolute or relative contra-indications for spinal anaesthesia e.g. infection in lumbar area, coagulation abnormalities, autonomic neuropathy, spinal deformities, other neurological diseases or hypovolemia due to any cause

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Estimated blood loss during intraoperative periodTimepoint: At the end of surgery
Secondary Outcome Measures
NameTimeMethod
Adequacy of uterine tone, Need for additional uterotonics, <br/ ><br>Change in haemoglobin level at 4 and 24 hours, <br/ ><br>Any oxytocin related side-effectsTimepoint: During surgery and till 24 hours after surgery
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