A Comparison of Intrathecal Morphine with Intravenous Patient Control Analgesia (IV PCA) for Pain Control After Video-Assisted Thoracoscopic Surgery (VATS)

Phase 4

Completed

• Conditions: The patients undergoing elective VATS; video- assisted thoracoscopic surgery; intrathecal morphine; pain; pruritus; morphine

• Registration Number: TCTR20201005002
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-05-12
• Study Start: 2020-10-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

1. Patients undergoing elective VATS
2. aged over 18 years
3. ASA physical status I to III.

Exclusion Criteria

1. unwillingness and/or inability to provide written informed consent to participate in the study,
2. pregnancy
3. contraindication to spinal block,
4. history of allergy to opioid
5. Receiving opioid therapy for chronic pain
6. History of severe postoperative nausea and vomiting (PONV),
7. History of previous surgical intervention at spinal T12-L5 level or significant spinal deformity,
8. Learning difficulty or communication problems, and
9. Retaining endotracheal tube after the operation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain 1st, 6th, 12th, 24th, 48th hours post-operation 11‐point numeric pain rating scales (NRS) that runs from 0-10

Secondary Outcome Measures

Name	Time	Method
Dose of morphine given as intravenous patient-controlled analgesia (IVPCA), 1st, 6th, 12th, 24th, 48th hours post-operation Dose of morphine in milligram ,Incidence of common side effects 3-point ordinal scale (0 = no symptom, 1 = having symptom without treatment, and 2 = having symptom report of post operative Nausea/vomiting, and pruritus PONV and pruritus,patient sedation 1st, 6th, 12th, 24th, 48th hours post-operation 5-point sedation Ramsay's score