MedPath

Preoperative Strength-resistance Training in Valvular Heart Disease Patients

Not Applicable
Not yet recruiting
Conditions
Exercise Based Prehabilitation in Valvular Surgery
Interventions
Other: Exercise based prehabilitation
Registration Number
NCT05911191
Lead Sponsor
Cardenal Herrera University
Brief Summary

Cardiovascular diseases (CVD) are a group of illnesses that include coronary heart disease, cerebrovascular disease, congenital heart disease, and deep vein thrombosis. CVD is the leading cause of mortality worldwide, representing 31% of deaths. In Spain, CVD caused 24% of all deaths in 2020. Major surgery is often chosen as the treatment of choice for CVD. The concept of fast-track rehabilitation after surgery appeared in the 1970s. Participation in these exercise-based prehabilitation programs may decrease postoperative complications and length of hospital stay.

The purpose of the present study is to evaluate whether the implementation of an additional resistance training (RT) prehabilitation protocol within a cardiac exercise-based prehabilitation can reduce ICU length of stay, postoperative complications, and hospital length of stay (LOS). Additionally, the secondary objective is to determine whether a program that includes RT in addition to respiratory and aerobic training can have better effects on ventilatory variables.

This study follows the protocol of a prospective, parallel, non-randomized clinical trial. Ninety-six adult patients diagnosed with valvular pathology and who have been scheduled for surgery will be included. The control group will be treated with ventilatory and strengthening of respiratory muscles, as well as aerobic exercise. The experimental group, in addition, will receive RT targeting peripheral muscles. Variables such as hospital stay, quality of life, respiratory values, and exercise capacity will be evaluated. Quantitative variables will be analyzed using a t-test or ANOVA, or Mann-Whitney test if the distribution is non-parametric.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
96
Inclusion Criteria
  • adult patients diagnosed with valvular pathology who have been admitted as candidates for cardiac surgery for the first time, and who have been scheduled for surgery
Exclusion Criteria
  • stage 4 or 5 renal failure, low ejection fraction, Euroscore greater than 15 (Nashef et al., 2012) , non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary artery disease, or need for urgent intervention

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ExperimentalExercise based prehabilitationAddittionally, a preoperative musculoskeletal and cardiopulmonary rehabilitation program focused on peripheral resistance training, will be implemented in the experimental group
Primary Outcome Measures
NameTimeMethod
EuroQoL-5D1 year

Perception of quality of life

Length of stay in ICU1 year

length of ICU stay from admission until the transfer of the patient to his room

length of stay in hospital1 year

length of hospital stay from admission to discharge

Secondary Outcome Measures
NameTimeMethod
Peak expiratory flow1 year

the maximum flow that a person can exhale during a brief maximal expiratory effort after full inspiration

Respiratory pressures1 year

the strength of the respiratory muscles, both at diaphragmatic (inspiratory) and abdominal and intercostal (expiratory) levels

Exercise capacity1 year

Patient's ability to perform physical exertion

Inspiratory capacity1 year

the volume of air that can be inspired by the resting inspiratory position

Trial Locations

Locations (1)

Hospital Universitario de La Ribera, Alzira

🇪🇸

Alzira, Valencia, Spain

Hospital Universitario de La Ribera, Alzira
🇪🇸Alzira, Valencia, Spain
© Copyright 2025. All Rights Reserved by MedPath