跳至主要内容
临床试验/CTRI/2023/11/059500
CTRI/2023/11/059500尚未招募1 期

Echocardiographic study of Left Ventricular diastolic dysfunction in Type 2 Diabetes Mellitus patients and correlation with hba1c levels.

Kodukula Naga Venkat Bharath1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年11月11日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
Diabetes mellitus type 2 is associated with left ventricular diastolic dysfunction.

研究概览

简要总结

This study aims to find out the incidence of Left ventricular diastolic dysfunction in patients with Diabetes mellitus type 2. Patients can be newly diagnosed or have a history of DMt2. At presentation all the participants will be tested with serum HbA1c levels which gives us an idea of blood sugar control for the past 3 months. Then the patient will go on to have a 2d echocardiography done, where in parameters for diastolic dysfunction will be measured.  Presence or absence of Diastolic dysfunction will be determined by recommendations made by American society of Echocardiography and European Association of cardiovascular Imaging in 2016. The diastolic dysfunction if present will be graded as mild , moderate or Severe and compared to the earlier HbA1c levels.  There will be another comparison of severity of diastolic dysfunction between smoking and non smoking Diabetic patients.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
50.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Patients with DM type 2 .Cases were selected as per the diagnostic criteria laid down by the American Diabetes Association.
  • Fasting blood glucose (FBS) of 126 mg/dl or higher or a 2-hr postprandial blood glucose (PPBS) level of 200 mg/dl or higher during a 75-gm oral glucose tolerance test or random plasma glucose of 200 mg/dl or higher in a patient with symptoms of hyperglycemia or HbA1c 6.5% or higher.

排除标准

  • Patients with systemic hypertension, coronary artery disease, ischemic heart disease, cardiomyopathy, valvular disorders, connective tissue disorder, CLD, CKD and thyroid dysfunction.

结局指标

主要结局

Diabetes mellitus type 2 is associated with left ventricular diastolic dysfunction.

时间窗: Baseline

次要结局

  • Smoking worsens diastolic dysfunction in diabetic patients(Baseline)

研究者

发起方
Kodukula Naga Venkat Bharath
申办方类型
Other [self]

研究点 (1)

Loading locations...

相似试验

Cardiac dysfunction in Diabetic patients. | 临床试验