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Influence of Acupuncture to Ocular Microcirculation in Patients With Diabetes Mellitus

Phase 2
Conditions
Diabetes Mellitus, Type 2
Interventions
Procedure: acupuncture
Registration Number
NCT01022177
Lead Sponsor
Technische Universität Dresden
Brief Summary

The purpose of this study is to determine the influence of specific eye acupuncture to the ocular microcirculation in diabetic and healthy subjects.

Detailed Description

Diabetes is combined with severe vascular damage at the different stages of the disease, causing reduction in retinal perfusion. Acupuncture is supposed to regulate the perfusion. We propose a study to evaluate the effect of acupuncture to the vascular auto regulation in patient with Diabetes, compared to healthy people without vascular or retinal diseases. The perfusion of the retinal vessel will be examined by Retinal vessel analyzer (RVA), Heidelberg retinal Flowmeter (HRF) and the Ocular blood Flowmeter (OBF) before, during and after standardized specific acupuncture at healthy volunteers and patients with diabetes.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
40
Inclusion Criteria
  • persons over 18 years, men or women, diabetic diagnostics within the last year
Exclusion Criteria
  • medical use of anticoagulative substances, use of dorzolamide, use of immunosuppressive medication
  • psychiatrics, epileptics

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
diabeticsacupuncturesubjects with HbA1c \>7,0 and pathological glucose tolerance testing
healthyacupuncturehealthy subjects with HbA1c \<7,0 and negative glucose tolerance testing
Primary Outcome Measures
NameTimeMethod
retinal perfusion by HRF/OBF/RVApost acupuncture (one day measurement)
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University Carl Gustav Carus

🇩🇪

Dresden, Saxonia, Germany

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