Treatment of patients with amiodarone-induced thyrotoxicosis type 2
Completed
- Conditions
- Amiodarone-induced thyrotoxicosis type 2Nutritional, Metabolic, EndocrineThyrotoxicosis [hyperthyroidism]
- Registration Number
- ISRCTN06558177
- Lead Sponsor
- Academic Medical Centre (AMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1. Thyroid stimulating hormone (TSH) less than 0.4 mE/L
2. Free thyroxine (FT4) greater than 25 pmol/l
3. Normal or raised triiodothyronine (T3)
4. Thyroid peroxidase antibodies less than 50 kU/l
5. Thyroid binding inhibitory immunoglobulins (TBII) less than 2.0 kU/l
6. Amiodarone use
7. Poor or no visualisation of thyroid gland on 99mTc-pertechnetate scintigraphy
8. No nodular goiter on ultrasound
Exclusion Criteria
1. Very critical illness
2. Drug or alcohol abuse
3. Pregnancy
4. No informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method