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Clinical Trials/NCT03750344
NCT03750344
Completed
Not Applicable

ChroniSense Polso Wrist Worn Respiration Rate Validation Study

ChroniSense Medical Ltd.1 site in 1 country20 target enrollmentNovember 6, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Rate
Sponsor
ChroniSense Medical Ltd.
Enrollment
20
Locations
1
Primary Endpoint
Respiratory Rate Accuracy of Polso Monitoring System
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

20 volunteer test subjects will be entered into an accuracy study that is designed to validate accuracy of the respiratory rate of the Polso Monitoring system

Detailed Description

20 volunteer test subjects will be entered into an accuracy study that is designed to validate accuracy of the respiratory rate of the Polso Monitoring system. A range of stable respiratory rates will be elicited from each volunteer test subject. The rates will be approximately 5, 10, 15, 20, 25, 30, 35, 40 and 45 breaths per minute; with some natural variation from these exact numbers. Each subject will be instrumented with an open system mask that allows for measurement of the end tidal carbon dioxide (EtCO2) respiratory rate and tidal volume. The EtCO2 monitor will be used as the Accuracy Reference Device (Reference) in this study.

Registry
clinicaltrials.gov
Start Date
November 6, 2018
End Date
November 30, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Subject must have the ability to understand and provide written informed consent
  • Subject is adult over 18 years of age
  • Subject must be willing and able to comply with study procedures and duration
  • Subject is a non-smoker
  • Male or female of any race
  • Wrist circumference with the range of 5.5-8 inches (13 to 21cm)

Exclusion Criteria

  • Subject is considered as being morbidly obese (defined as BMI \>39.5)
  • Compromised circulation, injury, or physical malformation of fingers, toes, hands, ears or forehead/skull or other sensor sites which would limit the ability to test sites needed for the study. Tattoo in the optical path which would limit the ability to test sites needed for the study.
  • Subjects with known respiratory conditions such as:
  • uncontrolled / severe asthma,
  • pneumonia / bronchitis,
  • shortness of breath / respiratory distress,
  • respiratory or lung surgery,
  • emphysema, COPD, lung disease
  • Subjects with self-reported heart or cardiovascular conditions such as:
  • have had cardiovascular surgery

Outcomes

Primary Outcomes

Respiratory Rate Accuracy of Polso Monitoring System

Time Frame: Through study completion, 1 month average

Respiratory Rate of test subject as compared to CO2 of End Tidal Carbon. Twenty second periods will be averaged to provide one respiratory rate value. Each stable respiratory rate plateau will result in four of these respiratory rate values which will be included in the ARMS calculation. The endpoint of interest is accuracy as measured by the Accuracy root-mean-square (Arms) difference between the device under test (DUT) and the reference respiratory rate system (Ref) for all stable respiratory periods. Acceptance criteria ARMS \<3

Study Sites (1)

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