ISRCTN58905233Completed未知
Apolipoprotein B and low density lipoprotein size in type two diabetes: effect of atorvastatin and gemfibrozil
Hospital Sant Pau (Spain)0 sites44 target enrollmentStarted: April 24, 2007Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 44
Study Overview
Brief Summary
2003 Results article in http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12843167
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Men and women with type two diabetes, aged 35 to 75 years
- •2. No treatment known to interfere with lipid metabolism (nonselective B-blockers, high dose diuretics, systemic steroids, lipid-lowering drugs) in the month preceding inclusion in the study
- •3. Plasma Low Density Lipoprotein cholesterol (LDLc) greater than 100 mg/dl (2.6 mmol/litre), and triglycerides less than 400 mg/dl (4.51mmol/litre)
Exclusion Criteria
- •1. Pregnant
- •2. No reliable contraceptive method was used
- •3. Serum creatinine more than 1.7 mg/dl (150 umol/litre)
- •4. Hepatic dysfunction (transaminases greater than 1.5 times upper normal limit at inclusion)
- •5. Creatine kinase more than three times the upper normal limit
- •6. Acute or chronic disorders that might interfere with compliance
Investigators
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