JPRN-UMIN000032027招募中未知
Elucidation of the pathophysiological mechanism of dementia and clinical research for creation of drug discovery targets - Elucidation of the pathophysiological mechanism of dementia
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 500
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. When a cerebral infarction or a local lesion which affects infection or cognitive function is found by MRI at screening. Small infarcts in the deep area and diffuse changes in the white matter allow incorporation except those occurring in specific sites affecting cognitive function, but in principle cortical infarction is excluded. 2. There is a problem to take a MRI imaging due to pacemaker, aneurysm clip, artificial valve, cochlear implant or other magnetic or electrically conductive metal, or claustrophobia. 3. If you have psychiatric symptoms, excitability, behavior abnormalities that make it difficult to follow the protocol within the past 3 months. 4. When suffering from severe systemic disease or unstable disease. 5. There are abnormalities affecting cognitive function in vitamin B 12 deficiency, syphilis, thyroid function. 6. When performing lumbar puncture, if you are taking antiplatelet medications, take the following drug withdrawal period into consideration before the examination. 7. Subject is participating in any treatment drug trials. 8. It is clear that participation in clinical trials of Alzheimer's disease treatment drug is made during the 3-year research period. 9. When taking a combination prohibited medicine such as warfarin. 10. Huntington's disease, multiple cerebral infarction, normal pressure hydrocephalus, brain tumor, epilepsy, paroxysmal disease, subdural hematoma, multiple sclerosis. 11. When there is a history of juvenile onset normal schizophrenia. 12. It is judged by the attending physician not to be appropriate.
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