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Clinical Trials/NCT04221386
NCT04221386
Suspended
Not Applicable

Melodic Intonation Therapy for Tone Language Speakers

The Hong Kong Polytechnic University1 site in 1 country40 target enrollmentAugust 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dementia
Sponsor
The Hong Kong Polytechnic University
Enrollment
40
Locations
1
Primary Endpoint
Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery
Status
Suspended
Last Updated
6 years ago

Overview

Brief Summary

One of the traditional therapies for restoring the ability of speech in aphasic patients is Melodic Intonation Therapy (MIT), in which everyday phrases are taught in a singing-like manner. The suggested mechanism for speech recovery is that because of the sharing of brain resources for language and music, the regions normally reserved for singing can be trained to help compensate the speech functions originally subserved by the damaged regions. However, this therapy has primarily been applied to speakers of non-tone languages, in which prosodic features carry a more important role than pitch features in conveying meanings. It remains unknown whether MIT will be equally applicable for speakers of tone languages, in which pitch features likely play a more important role. Another uncertainty concerns whether the efficacy of MIT can be extended to patients with expressive speech impairment due to dementia. This pilot study aims to find out the efficacy of MIT for speech-impaired dementia patients in different verbal tasks. The results of this study will provide preliminary empirical evidence to establish the utility of MIT for Cantonese speakers in Hong Kong.

Registry
clinicaltrials.gov
Start Date
August 1, 2020
End Date
February 28, 2021
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Early to moderate stage dementia patient
  • Normal hearing (hearing aid accepted)
  • Non-fluent speech (max. score of fluency in Cantonese Aphasia Battery spontaneous speech subtest = 6/10)

Exclusion Criteria

  • Non-native Cantonese speaker
  • Illiterate
  • Aphasic patients
  • Subjects who receive other speech therapy during study

Outcomes

Primary Outcomes

Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery

Time Frame: within a week after procedure

Two subtests of the Cantonese Aphasia Battery (auditory comprehension \& spontaneous speech) will be executed. Higher AQ means better performance in the respective areas. The minimum of AQ in each subtest is 0, and the maximum is 20.

Secondary Outcomes

  • Change in latency and accuracy in picture naming task(within a week after procedure)
  • Change in performance of semantic fluency task(within a week after procedure)

Study Sites (1)

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