Melodic Intonation Therapy for Tone Language Speakers

Not Applicable

Suspended

• Conditions: Speech Therapy; Dementia
• Interventions: Behavioral: Melodic Intonation Therapy (MIT)

• Registration Number: NCT04221386
• Lead Sponsor: The Hong Kong Polytechnic University

Brief Summary

One of the traditional therapies for restoring the ability of speech in aphasic patients is Melodic Intonation Therapy (MIT), in which everyday phrases are taught in a singing-like manner. The suggested mechanism for speech recovery is that because of the sharing of brain resources for language and music, the regions normally reserved for singing can be trained to help compensate the speech functions originally subserved by the damaged regions. However, this therapy has primarily been applied to speakers of non-tone languages, in which prosodic features carry a more important role than pitch features in conveying meanings. It remains unknown whether MIT will be equally applicable for speakers of tone languages, in which pitch features likely play a more important role. Another uncertainty concerns whether the efficacy of MIT can be extended to patients with expressive speech impairment due to dementia. This pilot study aims to find out the efficacy of MIT for speech-impaired dementia patients in different verbal tasks. The results of this study will provide preliminary empirical evidence to establish the utility of MIT for Cantonese speakers in Hong Kong.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-12
• Study First Submitted: 2020-01-03
• Study First Submitted QC: 2020-01-06
• Study First Posted: 2020-01-09
• Last Update Submitted: 2020-04-08
• Last Update Posted: 2020-04-10
• Study Start: 2020-08-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-02-28

Recruitment & Eligibility

• Status: SUSPENDED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Early to moderate stage dementia patient
• Normal hearing (hearing aid accepted)
• Non-fluent speech (max. score of fluency in Cantonese Aphasia Battery spontaneous speech subtest = 6/10)

Exclusion Criteria

• Non-native Cantonese speaker
• Illiterate
• Aphasic patients
• Subjects who receive other speech therapy during study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MIT group	Melodic Intonation Therapy (MIT)	Subjects will receive the developed Melodic Intonation Therapy.

Primary Outcome Measures

Name	Time	Method
Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery	within a week after procedure	Two subtests of the Cantonese Aphasia Battery (auditory comprehension \& spontaneous speech) will be executed. Higher AQ means better performance in the respective areas. The minimum of AQ in each subtest is 0, and the maximum is 20.

Secondary Outcome Measures

Name	Time	Method
Change in latency and accuracy in picture naming task	within a week after procedure	In the computerized picture naming task, subjects are asked to name the objects they see in 52 pictures, within 5000 ms per picture. Visual stimuli of the task are black and white line-drawings. Responses are all recorded for analysis.
Change in performance of semantic fluency task	within a week after procedure	In the computerized semantic fluency task, subjects are given 5 categories (e.g. animals) and asked to name as many members of the categories (e.g. cat, dog) as possible. For each category, they have one minute to respond. All the responses are recorded for analysis.

Trial Locations

Locations (1)

Elderly homes; 🇭🇰 Hong Kong, Hong Kong