A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients With Weakened Immune Systems
- Conditions
- HIV InfectionsChickenpox
- Registration Number
- NCT00002315
- Lead Sponsor
- Glaxo Wellcome
- Brief Summary
To determine the efficacy of oral 882C87 compared with oral acyclovir in the treatment of localized herpes zoster in immunocompromised patients. To assess the safety and tolerance of oral 882C87 in immunocompromised patients.
- Detailed Description
Patients are randomized to receive either 882C87 or acyclovir with corresponding placebos for 14 days, with two hundred patients in each of the two groups. They are stratified by presence or absence of HIV infection. Patients undergo 6 months of follow-up.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (25)
Cedars Sinai Med Ctr
🇺🇸Los Angeles, California, United States
N Texas Ctr for AIDS & Clin Rsch
🇺🇸Dallas, Texas, United States
Univ TX Med Branch
🇺🇸Nassau Bay, Texas, United States
Washington Univ
🇺🇸St. Louis, Missouri, United States
Simon - Williamson Clinic
🇺🇸Birmingham, Alabama, United States
Silver Lake Med Inc
🇺🇸Providence, Rhode Island, United States
Saint Francis Mem Hosp
🇺🇸San Francisco, California, United States
AIDS Community Research Consortium
🇺🇸Redwood City, California, United States
SORRA / NC Research Ctr
🇺🇸Birmingham, Alabama, United States
Sunnyvale Med Clinic
🇺🇸Sunnyvale, California, United States
Roger Williams Med Ctr
🇺🇸Providence, Rhode Island, United States
Med Associates Clinic
🇺🇸Dubuque, Iowa, United States
New Mexico Med Group
🇺🇸Albuquerque, New Mexico, United States
Clinical Research Consultants
🇺🇸Trumbull, Connecticut, United States
Oschner Clinic
🇺🇸New Orleans, Louisiana, United States
Infections Ltd / Physicians Med Ctr
🇺🇸Tacoma, Washington, United States
Med Consultants LTD
🇺🇸Milwaukee, Wisconsin, United States
MacGregor Med Association
🇺🇸Houston, Texas, United States
Univ of Arizona / Univ Med Ctr
🇺🇸Tucson, Arizona, United States
Hanover Med Specialists
🇺🇸Wilmington, North Carolina, United States
Oregon Health Sciences Univ
🇺🇸Portland, Oregon, United States
Jordon Diagnostics and Research Inc
🇺🇸High Point, North Carolina, United States
Vanderbilt Med Ctr
🇺🇸Nashville, Tennessee, United States
Oregon Research Group
🇺🇸Eugene, Oregon, United States
Rhinelander Med Ctr
🇺🇸Rhinelander, Wisconsin, United States