Effect of Smoking Cessation on Tuberculosis Treatment Outcomes
- Conditions
- Tuberculosis, Pulmonary
- Interventions
- Behavioral: Behavioural Change Communication
- Registration Number
- NCT04848246
- Lead Sponsor
- Dow University of Health Sciences
- Brief Summary
This study was a Randomized Controlled Trial conducted at Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, among pulmonary tuberculosis patients
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 292
- pulmonary tuberculosis patients of age 18 years or above
- registered under Directly Observed Treatment Short course (DOTS) at Ojha Institute of Chest Diseases
- reported to have smoked 100 plus cigarettes in past and currently smoking cigarettes
- Extra pulmonary tuberculosis
- drug resistant tuberculosis
- pregnancy
- positive history of epilepsy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Bupropion Behavioural Change Communication - Behavioural Change Communication Behavioural Change Communication - Bupropion Bupropion -
- Primary Outcome Measures
Name Time Method Percentage of patients completing anti-tuberculosis treatment six months Among both smear positive and smear negative TB patients, successful completion of ATT will be labeled at the end of 6 months period if the patients has been compliant with ATT through six months period..
- Secondary Outcome Measures
Name Time Method Percentage of participants achieving abstinence from smoking six months Abstinence is defined as staying away from smoking and it will be assessed at week 1, week 4, week 12 and week 24 will be assessed in following two ways:
i. Self-reported abstinence using questionnaire ii. Expired carbon monoxide (eCO) levels using Micro Smokerlyzer (Bedfont Scientific) of less than 7 ppm.
Trial Locations
- Locations (1)
Dow University of Health Sciences
🇵🇰Karachi, Sindh, Pakistan