Efficacy and Safety of 1L Polyethylene Glycol plus Low-dose Ascorbic Acid Compared to D-Sorbitol and Picosulfate plus Ascorbic Acid
- Conditions
- Factors influencing health status and contact with health services
- Registration Number
- KCT0009000
- Lead Sponsor
- Chung-Ang Univerisity Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 200
The following are the inclusion criteria for patients eligible to participate in the study:
Adult men and women aged 19 years and above.
Patients scheduled to undergo colonoscopy for screening or diagnostic purposes at the Gastroenterology outpatient departments of Chung-Ang University Hospital and Chung-Ang University Gwangmyeong Hospital from the start of the study.
Patients who have provided informed consent to participate in the study.
The following are the criteria for excluding patients from participating in the study:
1. Patients with functional or anatomical gastrointestinal obstructions (such as gastric paresis, pyloric stenosis, functional bowel obstructions, toxic megacolon, etc.), active gastrointestinal bleeding, or intestinal perforation.
2. Patients with dehydration, severe vomiting, or severe diarrhea.
3. Patients with a history of or current inflammatory bowel disease (Crohn's disease or ulcerative colitis) or those strongly suspected of having such conditions.
4. Patients with confirmed gastric ulcers.
5. Patients with a known history of intestinal adhesions that require surgery, or those in an acute abdominal condition requiring surgical intervention.
6. Patients with a history of previous gastrointestinal resection surgery (excluding appendectomy).
7. Patients with a history of glucose-6-phosphate dehydrogenase deficiency.
8. Patients with significant cardiovascular diseases (New York Heart Association classification III and IV), respiratory diseases, kidney disease (creatinine clearance <30mL/min), liver disease, or a combination of these conditions.
9. Patients with dementia, cognitive impairment, or altered consciousness.
10. Patients with a history of cardiac arrest.
11. Patients with known hypersensitivity or allergic reactions to the medications used.
12. Pregnant and lactating women.
13. Patients who do not provide informed consent for the study.
14. Other patients deemed unsuitable for the study by the principal investigator or study personnel.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proper bowel preparation status among groups
- Secondary Outcome Measures
Name Time Method Cecal intubation time, withdrawal time, polyp detection rate, adenoma detection rate, safety of bowel preparation agents, tolerability, compliance, satisfaction