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A study to Assess the Efficacy of Luteolin Gel as an Adjuvant Therapy in the Treatment of Periodontitis.

Phase 2
Conditions
Health Condition 1: K053- Chronic periodontitis
Registration Number
CTRI/2024/05/067436
Lead Sponsor
JSS Academy of Higher Education and Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Chronic periodontitis patients with minimum 20 remaining teeth.

Periodontal pocket depth of minimum 4 – 6 mm and/ or CAL of 1 to 4 mm.

Exclusion Criteria

Unwilling patients.

Systemic diseases having an impact on periodontium.

Patients on medications known to affect the periodontium.

Pregnant and lactating women.

Smokers.

Use of antibiotics within the Past 3 months.

Periodontal therapy within the Past 6 months.

Use of NSAID within the past 1 month.

Subjects with oral mucosal lesions.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Periodontal Clinical parametersTimepoint: Baseline, 3 weeks post-treatment, 3 months post-treatment
Secondary Outcome Measures
NameTimeMethod
Estimation of IL-6 level in Gingival Crevicular FluidTimepoint: Baseline, 3 weeks post-treatment, 3 months post-treatment
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