this trial is being conducted to see the effect of small dose of dexamethasone drug if given intravenously before surgery in reducing pain, vomiting and fatigue in patients undergoing laparoscopic cholecystectomy
Not Applicable
- Conditions
- Health Condition 1: null- All the patients planned for elective laparoscopic cholecystectomy between 18-70yrs
- Registration Number
- CTRI/2017/11/010318
- Lead Sponsor
- Maharishi Markandeshwar Institute of Medical Science and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All the patients admitted and planned for elective laparoscopic cholecystectomy presenting in of Department of Surgery.
Patients with both the sex fit for uncomplicated LC
Exclusion Criteria
Acute cholecystitis
Pregnancy
Patient having papillotomy by ERCP within one month
Patients having preoperative nausea & vomiting
Patients with hepatic and renal insufficiency
History of corticosteroid hypersensitivity
Patient receiving corticosteroids or immunosuppressive drugs
Patients will be excluded if converted from Laparoscopic cholecystectomy to open procedure
Any contraindiction of dexamethasone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the efficacy of pre operative i.v dexamethasone 8mg on Post operative nausea and vomiting <br/ ><br>To evaluate the efficacy of pre operative i.v dexamethasone 8mg on analysis Pain and Fatigue on the basis of visual analogue scale and self reported registration <br/ ><br>To evaluate the efficacy of pre operative i.v dexamethasone 8mg on levels C-Reactive proteinTimepoint: at 0-1 hr <br/ ><br>at 1-2 hr <br/ ><br>at 2-3 hr <br/ ><br>at 3-6 hr <br/ ><br>at 6-24 hr <br/ ><br>at 24-48 hr <br/ ><br>at 3rd day
- Secondary Outcome Measures
Name Time Method comperative evaluation of dexamethasone group with placeboTimepoint: at 0-1 hr <br/ ><br>at 1-2 hr <br/ ><br>at 2-3 hr <br/ ><br>at 3-6 hr <br/ ><br>at 6-24 hr <br/ ><br>at 24-48 hr <br/ ><br>at 3rd day