CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction

Completed

• Conditions: Long-term Major Cardiovascular Events; Percutaneous Coronary Intervention; Myocardial Infarction

• Registration Number: NCT02385682
• Lead Sponsor: Kiyuk Chang

Brief Summary

The purpose of this registry is to evaluate long-term clinical events in patients with acute myocardial infarction who were treated with percutaneous coronary intervention.

Although numerous articles have been published by using nationwide Korean myocardial infarction registries, such as the Korea Acute Myocardial Infarction Registry (KAMIR), limitation of previous registries is that these have little data beyond the first year of MI. Therefore, current registry was designed to assess long-term clinical events in patients with acute myocardial infarction.

Because most of myocardial infarction patients were treated by revascularization in real world of Korea, this registry limits the inclusion criteria to patients who were treated with percutaneous coronary intervention to reduce the bias.

Detailed Description

Cardiovascular center with high-volume percutaneous coronary intervention of following hospitals were participated.

* Seoul St. Mary's Hospital, Seoul, South Korea

* Yeoido St. Mary's Hospital, Seoul, South Korea

* Uijongbu St. Mary's Hospital, Gyeonggi-do, South Korea

* St. Paul Hospital, Seoul, South Korea

* Bucheon St. Mary's Hospital, Gyeonggi-do, South Korea

* Incheon St. Mary's Hospital, Incheon, South Korea

* St. Vincent Hospital, Gyeonggi-do, South Korea

* Deajon St. Mary's Hospital, Daejeon, South Korea

* Cheonnam University Hospital, Gwangju, South Korea

8 hospitals of the Catholic University of Korea already have web-based coronary intervention registry (NCT01239914). And Cheonnam University Hospital is one of leading hospitals to design and manage the web-based previous Korean nationwide myocardial infarction registry, such as such as the Korea Acute Myocardial Infarction Registry (KAMIR) (http://www.kamir.or.kr/).

All consecutive acute myocardial infarction patients had been enrolled in each registries prospectively.

Using these previous data, current registry update new clinical and angiographic variables and assess long-term clinical follow-up data retrospectively.

Study Timeline

• Study Start: 2004-01
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Study First Submitted: 2015-03-05
• Study First Submitted QC: 2015-03-10
• Study First Posted: 2015-03-11
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-16
• Last Update Posted: 2015-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4748

Inclusion Criteria

• Acute myocardial infarction who were treated with percutaneous coronary intervention

Exclusion Criteria

• Acute myocardial infarction who were managed by conservative strategy
• Acute myocardial infarction who were not treated with percutaneous coronary intervention

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse cardiac and cerebrovascular events	5 years

Secondary Outcome Measures

Name	Time	Method
Nonfatal myocardial infarction	5 years
Nonfatal stroke	5 years
Target lesion revascularization	5 years
Target vessel revascularization	5 years
Non-target vessel revascularization	5 years
Definite/Probable stent thrombosis	5 years
Hospitalization for heart failure	5 years
Bleeding defined as the Bleeding Academic Research Consortium (BARC) definitions type 2, 3, and 5	5 years
Bleeding defined as the thrombolysis In Myocardial Infarction (TIMI) major/minor	5 years
All-cause death	5 years
Cardiac death	5 years