CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Korean Patients With Acute Myocardial Infarction Registry (COREA-AMI)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 4,748
- 主要终点
- Major adverse cardiac and cerebrovascular events
研究概览
简要总结
The purpose of this registry is to evaluate long-term clinical events in patients with acute myocardial infarction who were treated with percutaneous coronary intervention.
Although numerous articles have been published by using nationwide Korean myocardial infarction registries, such as the Korea Acute Myocardial Infarction Registry (KAMIR), limitation of previous registries is that these have little data beyond the first year of MI. Therefore, current registry was designed to assess long-term clinical events in patients with acute myocardial infarction.
Because most of myocardial infarction patients were treated by revascularization in real world of Korea, this registry limits the inclusion criteria to patients who were treated with percutaneous coronary intervention to reduce the bias.
详细描述
Cardiovascular center with high-volume percutaneous coronary intervention of following hospitals were participated.
- Seoul St. Mary's Hospital, Seoul, South Korea
- Yeoido St. Mary's Hospital, Seoul, South Korea
- Uijongbu St. Mary's Hospital, Gyeonggi-do, South Korea
- St. Paul Hospital, Seoul, South Korea
- Bucheon St. Mary's Hospital, Gyeonggi-do, South Korea
- Incheon St. Mary's Hospital, Incheon, South Korea
- St. Vincent Hospital, Gyeonggi-do, South Korea
- Deajon St. Mary's Hospital, Daejeon, South Korea
- Cheonnam University Hospital, Gwangju, South Korea
8 hospitals of the Catholic University of Korea already have web-based coronary intervention registry (NCT01239914). And Cheonnam University Hospital is one of leading hospitals to design and manage the web-based previous Korean nationwide myocardial infarction registry, such as such as the Korea Acute Myocardial Infarction Registry (KAMIR) (http://www.kamir.or.kr/).
All consecutive acute myocardial infarction patients had been enrolled in each registries prospectively.
Using these previous data, current registry update new clinical and angiographic variables and assess long-term clinical follow-up data retrospectively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute myocardial infarction who were treated with percutaneous coronary intervention
排除标准
- •Acute myocardial infarction who were managed by conservative strategy
- •Acute myocardial infarction who were not treated with percutaneous coronary intervention
结局指标
主要结局
Major adverse cardiac and cerebrovascular events
时间窗: 5 years
次要结局
- All-cause death(5 years)
- Cardiac death(5 years)
- Target vessel revascularization(5 years)
- Nonfatal myocardial infarction(5 years)
- Nonfatal stroke(5 years)
- Target lesion revascularization(5 years)
- Non-target vessel revascularization(5 years)
- Definite/Probable stent thrombosis(5 years)
- Hospitalization for heart failure(5 years)
- Bleeding defined as the Bleeding Academic Research Consortium (BARC) definitions type 2, 3, and 5(5 years)
- Bleeding defined as the thrombolysis In Myocardial Infarction (TIMI) major/minor(5 years)
研究者
Kiyuk Chang
Chief of the division of cardiology
Seoul St. Mary's Hospital