Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up

• Conditions: Myocardial Infarction; Chronic Kidney Diseases; Cerebral Infarction; Mortality

• Registration Number: NCT03166696
• Lead Sponsor: Guangdong Provincial People's Hospital

Brief Summary

A registry of consecutive patients who were admitted and diagnosed with acute myocardial infarction or acute cerebral infarction were conducted at the Guangdong General Hospital or the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Yue Bei People's Hospital, China, between January 2000 and December 2016. The adverse clinical outcomes, including all-cause mortality, were followed from the date of admission for acute myocardial infarction or acute cerebral infarction until study end (December 31, 2016). All-cause mortality, including the date of death, was identified from the electronic hospitalization data, phone follow-up, and confirmed by the household registration (HUKOU) system, a record of registration required by law in China. Baseline characteristics, including major treatment of acute myocardial infarction or acute cerebral infarction, estimated glomerular filtration rate (eGFR) and proteinuria, were collected. Demographic data were determined from the electronic hospitalization data and electronic hospital discharge records. All comorbid conditions were identified using International Statistical Classification of Diseases, Tenth Revision (ICD-10), coding algorithms applied to electronic physician claims and electronic hospital discharge records. Life style (smoking), treatment regimen at discharge, including angiotensin-converting enzyme inhibitor (ACEI), angiotensin II receptor blocker (ARB), were determined from the electronic hospitalization data.

Detailed Description

Not available

Study Timeline

• Study Start: 2000-01-03
• Status Verified: 2017-05
• Study First Submitted: 2017-05-18
• Study First Submitted QC: 2017-05-24
• Last Update Submitted: 2017-05-24
• Study First Posted: 2017-05-25
• Last Update Posted: 2017-05-25
• Primary Completion: 2018-05
• Study Completion: 2018-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30000

Inclusion Criteria

• consecutive patients who were admitted and diagnosed with acute myocardial infarction or acute cerebral infarction

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Exclusion Criteria

• lacunar infarction

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
all-cause mortality	follow up until the study end (May 2018,Anticipated)	all-cause mortality

Secondary Outcome Measures

Name	Time	Method
kidney outcome	follow up until the study end (May 2018,Anticipated)	ESRD or 50%eGFR decline

Trial Locations

Locations (3)

Guangdong General Hospital; 🇨🇳 Guangzhou, Guangdong, China

the First Affiliated Hospital of Guangzhou University of Chinese Medicine; 🇨🇳 Guangzhou, Guangdong, China

Yue Bei People's Hospital; 🇨🇳 Shaoguan, Guangdong, China