Prolonged muscle protein synthetic response to the ingestion of a large amount of protei
- Conditions
- ot applicable
- Registration Number
- NL-OMON22927
- Lead Sponsor
- ot applicable
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
Male
-Aged between 18-40 years
-Healthy
-18.5 = BMI 30 = kg·m-2
Exclusion Criteria
-Smoking
-Sports/exercise > 4 sessions/week
-Lactose intolerant or allergies to milk protein
-A history of neuromuscular problems
-Use of anticoagulation medication
-Recent (<9 months) participation in amino acid tracer (L-[ring-2H5-phenylalanine, L-[ring-2H2]-tyrosine, and [1-13C]-leucine infusion) studies
-Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription acne medications).
-Strict vegetarian (because of standardized Aviko meal)
-Injury or condition that would limit the participant from performing the resistance exercise.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Myofibrillar protein synthesis rates
- Secondary Outcome Measures
Name Time Method Whole-body protein kinetics and metabolism, plasma metabolites (e.g. glucose and insulin), 1-13C-phenylalanine incorporation