The effects of cholesterol-lowering medication on exercise performance.
- Registration Number
- NL-OMON28167
- Lead Sponsor
- Department of Physiology, Radboudumc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 72
Inclusion Criteria
3 study groups:
1. Statin users with self-reported muscle symptoms
Exclusion Criteria
- Familial hypercholesterolemia
- History of cardiovascular event within 1 year of study participation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Exercise-induced change in aerobic fitness<br /><br>- Exercise-induced change in mitochondrial mass and function and substrate use<br>
- Secondary Outcome Measures
Name Time Method - Exercise-induced change in muscle strength, contractile function and fatigue, and muscle mass<br /><br>- Exercise-induced change in pain- and fatigue rating, and quality of life