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临床试验/NCT07207863
NCT07207863招募中不适用

The Cardiac and Panvascular Medicine Diagnosis and Treatment Center, People's Hospital of Xinjiang Uygur Autonomous Region,

People's Hospital of Xinjiang Uygur Autonomous Region1 个研究点 分布在 1 个国家目标入组 1,000,000 人开始时间: 2016年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
1,000,000
试验地点
1
主要终点
Infections diseases

研究概览

简要总结

This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.

详细描述

This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health.

The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Residents >=18y
  • •Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance
  • •Residents without severe physical disability and capable of normal communication
  • •Residents whose diseases and deaths are monitored and managed by the local health authorities
  • •Residents who voluntarily participate and provide written informed consent

排除标准

  • •Temporary residents or floating population
  • •Residents with severe health conditions that prevent participation in the study
  • •Residents who are unwilling to undergo follow-up assessments for the study

结局指标

主要结局

Infections diseases

时间窗: 20 years

Incident disease during follow-up

Haematological or immunological diseases

时间窗: 20 years

Incident disease during follow-up

Cancers

时间窗: 20 years

Incident disease during follow-up

Mortality

时间窗: 20 years

All-cause and cause-specific mortality during follow-up

Cardiovascular diseases

时间窗: 20 years

Incident disease during follow-up

Digestive diseases

时间窗: 20 years

Incident disease during follow-up

Endocrine diseases

时间窗: 20 years

Incident disease during follow-up

Respiratory diseases

时间窗: 20 years

Incident disease during follow-up

Benign neoplasm or Carcinoma in situ

时间窗: 20 years

Incident disease during follow-up

Genitourinary diseases

时间窗: 20 years

Incident disease during follow-up

Musculoskeletal diseases

时间窗: 20 years

Incident disease during follow-up

Neurological diseases

时间窗: 20 years

Incident disease during follow-up

Psychiatric diseases

时间窗: 20 years

Incident disease during follow-up

Ocular diseases

时间窗: 20 years

Incident disease during follow-up

Dermatological diseases

时间窗: 20 years

Incident disease during follow-up

Ear and mastoid disorders

时间窗: 20 years

Incident disease during follow-up

次要结局

未报告次要终点

研究者

发起方
People's Hospital of Xinjiang Uygur Autonomous Region
申办方类型
Other
责任方
Principal Investigator
主要研究者

Yining Yang

Prof.

People's Hospital of Xinjiang Uygur Autonomous Region

研究点 (1)

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