The Cardiac and Panvascular Medicine Diagnosis and Treatment Center, People's Hospital of Xinjiang Uygur Autonomous Region,
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000,000
- 试验地点
- 1
- 主要终点
- Infections diseases
研究概览
简要总结
This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.
详细描述
This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health.
The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Residents >=18y
- •Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance
- •Residents without severe physical disability and capable of normal communication
- •Residents whose diseases and deaths are monitored and managed by the local health authorities
- •Residents who voluntarily participate and provide written informed consent
排除标准
- •Temporary residents or floating population
- •Residents with severe health conditions that prevent participation in the study
- •Residents who are unwilling to undergo follow-up assessments for the study
结局指标
主要结局
Infections diseases
时间窗: 20 years
Incident disease during follow-up
Haematological or immunological diseases
时间窗: 20 years
Incident disease during follow-up
Cancers
时间窗: 20 years
Incident disease during follow-up
Mortality
时间窗: 20 years
All-cause and cause-specific mortality during follow-up
Cardiovascular diseases
时间窗: 20 years
Incident disease during follow-up
Digestive diseases
时间窗: 20 years
Incident disease during follow-up
Endocrine diseases
时间窗: 20 years
Incident disease during follow-up
Respiratory diseases
时间窗: 20 years
Incident disease during follow-up
Benign neoplasm or Carcinoma in situ
时间窗: 20 years
Incident disease during follow-up
Genitourinary diseases
时间窗: 20 years
Incident disease during follow-up
Musculoskeletal diseases
时间窗: 20 years
Incident disease during follow-up
Neurological diseases
时间窗: 20 years
Incident disease during follow-up
Psychiatric diseases
时间窗: 20 years
Incident disease during follow-up
Ocular diseases
时间窗: 20 years
Incident disease during follow-up
Dermatological diseases
时间窗: 20 years
Incident disease during follow-up
Ear and mastoid disorders
时间窗: 20 years
Incident disease during follow-up
次要结局
未报告次要终点
研究者
Yining Yang
Prof.
People's Hospital of Xinjiang Uygur Autonomous Region
