Regulation of microRNAs in progenitor cells of patients with coronary artery disease

• Conditions: I25; Chronic ischaemic heart disease

• Registration Number: DRKS00000232
• Lead Sponsor: Institute for Cardiovascular Regeneration,Centre of Molecular Medicine, Goethe-University Frankfurt

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with documented stable coronary artery disease. Written informed consent and willigness to give a sample of 20 ml venous blood.

Exclusion Criteria

- Active infection or fever
- Pregnancy or breastfeeding
- Chronic inflammatory disease (e.g. M. Crohn, Rheumatoid Arthritis)
- HIV infection or active hepatitis
- Neoplastic disease without documented complete remission within the past 5 years
- Apoplectic insult within the past 3 months
- Impaired renal function (creatinine >2.5 mg/dl) at the time of treatment
- Relevant liver disease (GOT >2 ULN, or spontaneous INR >1.5)
- Mental retardation
- Any condition that per investigator?s judgment increases the patient?s risk or excludes adequate collection of study data
- Participation in another clinical trial within the past 30 days

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection of microRNAs in progenitor cells of patients with coronary artery disease and in healthy controls.