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Adipose Inflammation and Diabetes (FAB)

Recruiting
Conditions
Obese
Registration Number
NCT04255264
Lead Sponsor
Göteborg University
Brief Summary

The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
18
Inclusion Criteria
  • BMI 30-40 kg/m2
  • Ptos (i.e. excess skin) > 3 cm
  • Patient underwent gastric bypass surgery >2 years ago
  • Patient has had a stable weight ≥6 months at the time of operation
  • Patient does not smoke (min 6 weeks prior to surgery)
Exclusion Criteria
  • Patients who do not understand spoken and written Swedish
  • American Society of Anesthesiologists (ASA) classification ≥ 3
  • Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
  • Preoperatively known hernia requiring surgical operation
  • Severe mental illness

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Inflammatory status2025

The inflammatory status will be studied in obese patients.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Sahlgrenska university hospital

🇸🇪

Gothenburg, Vastra Gotaland, Sweden

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