Assessment of Right Ventricular Function in Advanced Heart Failure: Feasibility and Reliability of Right Ventricular Elastance
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Dilated Cardiomyopathy
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
- Enrollment
- 60
- Locations
- 2
- Primary Endpoint
- Number of Participants with altered Right ventriculo/arterial (R-V/A) coupling over PAPm and Pulmonary Hypertension types
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
We examined the feasibility and reliability of a combined echocardiographic and right heart catheterization (RHC) approach for right ventriculo/arterial (R-V/A) coupling assessment in HF patients with dilated cardiomyopathy (D-CMP).
Detailed Description
This is a single center, retrospective cross-sectional study. In 2016-17, for 6 months, we evaluated for eligibility 81 consecutive D-CMP patients afferent to "Niguarda Great Metropolitan Hospital" for RHC and echocardiography. All participants underwent the exams in the context of heart-transplant or advanced HF evaluation. Inclusion criteria were: 18 years old, given informed consent, D-CMP, New York Heart Association (NYHA) functional class II or III and reduced EF (≤ 35%). On the contrary, exclusion criteria were: missing the inclusion criteria and refused informed consent. The final sample consisted of 68 study participants (mean age 64±7 years, 82 % male).
Investigators
Francesco Bianco
Principal Investigator
ITAB - Institute for Advanced Biomedical Technologies
Eligibility Criteria
Inclusion Criteria
- •18 years old
- •Given informed consent
- •New York Heart Association (NYHA) functional class II or III
- •Reduced EF (≤ 35%)
Exclusion Criteria
- •Missing the inclusion criteria
- •Refused informed consent
Outcomes
Primary Outcomes
Number of Participants with altered Right ventriculo/arterial (R-V/A) coupling over PAPm and Pulmonary Hypertension types
Time Frame: up to 24 weeks
Significant correlations and augmentation over PAPm and Pulmonay Hypertension
Secondary Outcomes
- Rate of agreement in Right ventriculo/arterial (R-V/A) coupling assessment(up to 24 weeks)