Amyloid pathology in cognitively normal elderly subjects
- Conditions
- dementiaAlzheimer's disease10042258
- Registration Number
- NL-OMON55380
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
- Age 60-100 years - Monozygotic twin - Telephone Interview for Cognitive
Status modified (TICSm) >22 - Geriatric Depression Scale (GDS) (15 item) <11 -
Consortium to Establish a Registry for Alzheimer*s Disease (CERAD) 10 word list
immediate and delayed recall (> -1.5 SD of age adjusted normative data) -
Clinical Dementia Rating (CDR) scale of 0 with a score on the memory subdomain
of 0
- clinical diagnosis of probable Alzheimer's disease or mild cognitive
impairment
- neurological problems like Parkinson's disease, Huntington disease, severe
head trauma, braintumour, stroke with physical impairment, epilepsy currently
using antiepileptic drugs, braininfection
- known uncontrolled diabetes, thyroid disease, vitamin B12 deficiency
- psychiatric disorder like psychosis or schizophrenia
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method