A pilot study to understand the mechanism of unexplained infertility
Not Applicable
- Conditions
- Health Condition 1: N979- Female infertility, unspecified
- Registration Number
- CTRI/2024/03/064431
- Lead Sponsor
- AIIMS Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Cases:
1.Women in reproductive age group (21-39yrs) with unexplained infertility.
2.Women with both primary or secondary infertility
3.No hormonal treatment for at least 6 months prior to study
4.No history of intra-uterine contraceptive use
Controls:
1.Women in reproductive age group (21-39yrs)
2.Fertile women visiting OPD for any gynaecological disorder requiring endometrial biopsy for diagnosis and treatment of of their pathology.
Exclusion Criteria
Patients with history of pelvic inflammatory diseases, pelvic surgery including caesarean section, unilateral tubal patency, ovarian hyperstimulation syndrome, diminished ovarian response, endometriosis or multiple female factors or any evidence of genital malignancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method understand if estrogen receptor expression and/ or epithelial to mesenchymal transition of the uterine tissue is associated with unexplained infetilityTimepoint: first visit/examination of uterine biopsy
- Secondary Outcome Measures
Name Time Method nderstand cause of infertilityTimepoint: baseline