ltrasound scanning with contrast enhancement to assess disease activity in Crohn's disease

Not Applicable

Completed

• Conditions: Oral and Gastrointestinal - Crohn's disease; Crohn's disease

• Registration Number: ACTRN12609000323224
• Lead Sponsor: Royal Perth Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-05-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with Crohn’s disease who are experiencing an exacerbation (Crohn’s disease activity index, CDAI >150) and who require a colonoscopy or flexible sigmoidoscopy

Exclusion Criteria

Pregnant and lactating women, patients with abdominal surgery during the past 6 months, known right-to-left intracardiac shunts, unstable cardiac disease, pulmonary hypertension, severe chronic obstructive pulmonary disease, pulmonary vasculitis and hypersensitivity to ultrasound contrast agents.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of quantitative parameters derived from time-intensity curve of contrast enhancement of bowel wall with clinical and endoscopic parameters of disease activity[Outcomes will be measured once at enrolment and once on the second visit approximately 4-6 weeks post enrolment.]

Secondary Outcome Measures

Name	Time	Method
Comparison of bowel wall thickness with clinical and endoscopic parameters of disease activity[Outcomes will be measured once at enrolment and once on the second visit approximately 4-6 weeks post enrolment.]