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MR Imaging of Lymphadenopathy in Rectal Cancer using the MR Agent Vasovist

Phase 2
Suspended
Conditions
bowel cancer
rectal cancer
10017991
Registration Number
NL-OMON31454
Lead Sponsor
Academisch Ziekenhuis Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Suspended
Sex
Not specified
Target Recruitment
90
Inclusion Criteria

Biopsy-proven rectal cancer
Age: at least 18 years
Surgery for rectal cancer planned within 60 days after Vasovist-enhanced MRI
Willing and able to undergo all study procedures
Written informed consent

Exclusion Criteria

Age < 18 years
Pregnant and/or nursing women
Contra-indication for MRI
Previous severe allergic reaction to MR-contrast agent
Allergy to any of the ingredients of VAsovist
History of previous malignancy

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Sensitivity, specificity, NPV and PPV of Vasovist®-enhanced MRI for detection<br /><br>lymph nodes with tumor infiltration (node-by node analysis)</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>na</p><br>
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