Implementation of eccentric training in various clinical populations - a pilot study

Not Applicable

Recruiting

• Conditions: M54; G35; Dorsalgia; Multiple sclerosis

• Registration Number: DRKS00020483
• Lead Sponsor: niversität Potsdam, Professur für Sportmedizin und Sportorthopädie/Hochschulambulanz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Control:
- Males and females 18-65 years old;

Low back pain group:
- Minimum of 3 low back pain episodes within last 12 months (but not exclusively within the last 3 months,
- Average Score of 3 or more for subjective pain within the last 3 months based on a 11-point pain rating scale (0: No pain; 10: maximal imaginable pain),
- Males and females 18-65 years old;

Multiples sclerosis:
- A neurologist-confirmed diagnosis of definite MS according to the revised McDonald criteria Exclusion criteria,
- <4.5 score on the Expanded Disability Status Scale (EDSS), the ability to walk an equivalent of at least 500m without a walking aid,
- Relapse-free for at least 90 days prior to testing
- Males and females 18-65 years old;

Exclusion Criteria

Control:
- Acute infections,
- Pregnancy,
- Structural changes of the spine with or without neurological signs which contra-indicate physical activities,
- Acute back pain,
- Back pain (>24h) within the last 12 months,
- Average Score of 3 or more for subjective pain within the last 3 months based on a 11-point pain rating scale (0: No pain; 10: maximal imaginable pain);

Low back pain:
- Acute infections,
- Pregnancy,
- Structural changes of the spine with or without neurological signs which contra-indicate physical activities,
- Acute back pain, which occurred for the first time within the last 7 days;

Multiple sclerosis:
- Pregnancy,
- Cardiovascular disorders,
- Respiratory disorders,
- Taking steroids or fampridine

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delta pre-post intervention for isokinetic peak force (dynamometer):<br>- Low back pain: maximal trunk force (trunk flexion and extension)<br>- Multiples sclerosis: maximal leg force (knee flexion and extension)

Secondary Outcome Measures

Name	Time	Method
Delta pre-post intervention for<br>(1) Clinical Mobility tests: <br>- „Timed Up and Go test; <br>- „5-times Chair Rise test;<br>(2) Postural control (COP measurements):<br>- Double-leg stance;<br>- Single-leg stance;<br>(3) Questionnaires:<br>- EQ-5D Health questionnaire;<br>- Low back pain: Graded Chronic Pain Scale Questionnaire (van Korff);<br>- Multiple Sclerosis: SF 36 quality of life in MS, Multiple Sclerosis Walking Scale (MSWS-12), Modified Fatigue Impact Scale (MFIS), Falls Efficacy Scale International (FES-I)