Effects of oxygen on the circulatory system and brain blood flow in experimental blood loss in helathy volunteers.

Phase 1

• Conditions: Hypovolemia is the condition under investigation. Hypovolemia is induced by the lower body negative pressure (LBNP)-model.; MedDRA version: 20.0Level: PTClassification code 10049771Term: Shock haemorrhagicSystem Organ Class: 10047065 - Vascular disorders; Therapeutic area: Body processes [G] - Physiological processes [G07]

• Registration Number: EUCTR2021-003238-35-NO
• Lead Sponsor: Oslo University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-22
• Last Update Posted: 8 August 2022

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

- Age > 18 years.
- Age < 50 years.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 15
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range 0

Exclusion Criteria

1.Any medical condition limiting physical exertional capacity or requiring regular medication (allergy and contraceptives excepted).
2.Pregnancy.
3.Breastfeeding.
4.History of syncope (syncope of presumed vasovagal nature with known precipitating factor excepted).
5.Any known cardiac arrhythmia.
Prior/Concomitant Therapy
6.Any drug (contraceptives excepted) used on a regular basis for a chronic condition (allergy excepted).

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified