Skip to main content
MedPathMedPath Home
Clinical Trials/IRCT20220315054298N1
IRCT20220315054298N1
Not Yet Recruiting
Phase 2

comparison of the Effectiveness of pre-operative intravenous ketamine administration with placebo in controlling post-operative pain in patients with advanced knee osteoarthritis undergoing total knee arthroplasty

Tehran University of Medical Sciences0 sites60 target enrollmentTBD
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
Tehran University of Medical Sciences
Enrollment
60
Status
Not Yet Recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Between 18 and 85 years old
  • •undergoing unilateral, primary total knee arthroplasty TKA for degenerative end\-stage osteoarthritis(OA) of the knee (score of \>2 on Kellgren\-Lawrence scale).

Exclusion Criteria

  • •patients who refuse to participate,
  • •classified as ASA IV or V by the American Society of Anesthesiologists,
  • •body mass index greater than 40 kg/m2,
  • •rheumatoid arthritis,
  • •contraindication or allergy to opioid pain medications
  • •allergy to amide or sulpha anesthetics,
  • •unable to understand the visual analog scale (VAS) ,
  • •any preoperative ketamine or chronic narcotic usage (\>10mg systemic morphine equivalents daily ) as it causes opioids tolerance ,
  • •those who are discharged before the first 24 hours postoperatively,
  • •previous history of knee arthroplasty,

Outcomes

Primary Outcomes

Not specified

Similar Trials

Recruiting
N/A
Comparison of the efficacy of the preoperative use of dienogest and gonadotropin releasing hormone agonist for endometriosis: A randomized controlled trialendometriosis
JPRN-UMIN000006469Obstetrics and Gynecology60
Completed
Phase 3
Comparison of the effects of Atropine and Tetracaine on Oculo Cardiac Reflex (OCR) in strabismus surgeryStrabismus.Other strabismus
IRCT20150106020588N8Esfahan University of Medical Sciences120
Not Yet Recruiting
N/A
A study to compare the effectiveness of dexmedetomidine and ketamine medications administered in mist form into the lungs before surgery in reducing sorethroat following thyroid operations under general anesthesia with endotracheal intubatioHealth Condition 1: O- Medical and Surgical
CTRI/2019/07/020082Amala Institute of Medical Sciences
Not Yet Recruiting
N/A
To assess the efficiency of 2 different pain killers, ibuprofen and etoricoxib on its ability to reduce the pain and inflammation during root canal treatment in teeth having pulplal inflammation.
CTRI/2022/12/048521Dr Adarsha M S
Not Yet Recruiting
Phase 2
comparing efficacy of preoperative magnesium sulphate nebulization with ketamine nebulization in reducing incidence of severity of post operative sore throat in patient undergoing surgery under general anesthesia.,Health Condition 1: O- Medical and SurgicalHealth Condition 2: O- Medical and Surgical
CTRI/2024/04/065794dr vaishnav