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effect of addition of clonidine to bupivacaine in transversus abdoninis plane block on postoperative pain after lower segment cesarean sectio

Not Applicable
Completed
Conditions
Health Condition 1: null- Healthy Parturients coming for LSCS under spinal anesthesia
Registration Number
CTRI/2013/10/004042
Lead Sponsor
ady Hardinge Medical College
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

100 healthy parturients (ASA physical status I and II) carrying a singleton fetus at term, scheduled to undergo elective LSCS under spinal anaesthesia, followed by a TAP block to relieve postoperative pain

Exclusion Criteria

Patients who refused spinal anaesthesia, had any contraindication to regional anaesthesia, had any major co-morbidity or if they were unable to communicate in either English or Hindi language were excluded from this study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome will be the duration of postoperative analgesia, defined as the time (in hours) from the giving of the bilateral TAP block with clonidine 1µgkg-1 with 0.25% bupivacaine 20 ml bilaterally or 0.25% bupivacaine 20ml alone to the time to first analgesic request in the postoperative period.Timepoint: time (in hours) from the giving of the bilateral TAP block with clonidine 1µgkg-1 with 0.25% bupivacaine 20 ml bilaterally or 0.25% bupivacaine 20ml alone to the time when patient first demands analgesia in the postoperative period.
Secondary Outcome Measures
NameTimeMethod
â?¢the total requirement of analgesics in the first 24hours postoperatively <br/ ><br>â?¢patients satisfaction and <br/ ><br>â?¢possible clonidine side effects (nausea and vomiting, sedation, dry mouth , hypotension & bradycardia)Timepoint: . after TAP block, observed every 30 minutes for the first 2 hours, then every hour for next 10 hours and thereafter every 2 hours till the patient demands first dose of analgesia.
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