Evaluation of Zinc Supplementation Taken Prior or With Food
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Plasma Zinc changes
研究概览
简要总结
The purpose of this study is to determine the influence of food consumption timing on the body's response to a zinc supplement
详细描述
This research is a dietary intervention study designed to evaluate the effect of the food consumption timing on the absorption of zinc supplement.
The main objective is to measure plasma zinc in generally healthy male subjects, who will consume zinc supplement with food or 30-min before food for 2-weeks.
In addition to the primary objectives, correlations in enzyme activity with changes in fat metabolism, namely circulating triglyceride and cholesterol, will be determined. This will enable the determination of the effect of a low Zn intake on various aspects of dyslipidemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
盲法说明
Random number used to label samples
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •willing to stop supplementation 4 weeks prior to start of the study
- •has an operative understanding of English
- •no plans to move from the area during the study period
- •regularly eat breakfast
排除标准
- •Chronic or acute metabolic disease
- •smoker or user of nicotine products
- •history of alcohol abuse, or use of illicit drugs (incl marijuana)
- •Is underweight or overweight, body mass index (BMI) < 18 or > 30 kg/m2
研究组 & 干预措施
supplement prior to food
Zinc supplement to be taken 30-min before breakfast consumption
干预措施: Zinc supplement (Dietary Supplement)
Supplement with food
Zinc supplement to be taken at time of breakfast consumption
干预措施: Zinc supplement (Dietary Supplement)
结局指标
主要结局
Plasma Zinc changes
时间窗: Day 0, Day 15
Change in plasma zinc
次要结局
- Body weight changes(Day 0, Day 15)
- Essential Fatty acid changes(Day 0, Day 15)
- Blood glucose changes(Day 0, Day 15)