se of 2-chloroprocaine by adding fentanyl and dexmedetomidine in short duration orthopaedic surgeries
- Conditions
- Health Condition 1: S80-S89- Injuries to the knee and lower leg
- Registration Number
- CTRI/2020/07/026388
- Lead Sponsor
- Sri Venkateswara Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients of American society of Anesthesiologists physical status grade 1 and 2
2. Patients of age group between 20 to 65 years
3. patients posted for elective lower limb orthopaedic surgeries with duration of 1.5 to 2 hrs
1. Patients who are not willing to participate in the study.
2. Patients who do not give consent for spinal anaesthesia.
3. H/o spinal surgeries.
4. H/o coagulation and bleeding disorders.
5. Local site infections.
6. H/o hypersensitivity to study drugs.
7. H/o uncontrolled HTN and DM & H/o CAD.
8. Increased serum creatinine and liver enzymes:
2-3 times of normal.
9. H/o neuropsychiatric disorders and communication problems
10. Patients who cannot understand visual analog scale (VAS) measurements.
11. Pregnant women and lactating mothers.
12. Height- <140 cm & BMI > 35 Kg/m2.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of analgesiaTimepoint: Time of the first analgesic request
- Secondary Outcome Measures
Name Time Method 1.Onset of sensory block <br/ ><br>2.Onset of motor block <br/ ><br>3.Height of the sensory block <br/ ><br>4.Duration of sensory block <br/ ><br>5.Duration of motor block <br/ ><br>6.Regression time below L1 <br/ ><br>7.VAS score of pain <br/ ><br>8.VAS score of patient satisfaction <br/ ><br>9.Adverse hemodynamic effects during the study period <br/ ><br> <br/ ><br>Timepoint: 0,3 min, 6 min, 9 min, 12 min, 15 min, 30 min, 45 min, 60 min, 2 hrs, 3 hrs and 4 hrs after injection of study drug. <br/ ><br>