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临床试验/NCT02530749
NCT02530749已完成不适用

Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor Patients

University of Colorado, Denver1 个研究点 分布在 1 个国家目标入组 265 人开始时间: 2014年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
265
试验地点
1
主要终点
Number of patients with a Complication risk

研究概览

简要总结

Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.

详细描述

Preoperative risk assessment is important, but inexact, in older patients because physiologic reserves are difficult to measure. This also makes an important difference related to brain tumor patients, who may be burdened with systemic disease, alterations in cognition, or affected by other comorbidities. When assessing quality of life for brain tumor patients, having a better predictor of postsurgical outcome would be beneficial in appropriately counseling these patients. Frailty is thought to estimate physiologic reserves, and its use has been found to predict postoperative complications, length of stay, and discharge to a skilled or assisted-living facility in neurosurgical patients. Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ambulatory (able to walk)
  • Scheduled for neurosurgical resection of brain tumor

排除标准

  • Parkinson disease
  • Previous stroke
  • Taking: carbidopa/levodopa, donepezil hydrochloride, or antidepressants

结局指标

主要结局

Number of patients with a Complication risk

时间窗: 30 days

Number of patients with a complication risk based on a Hopkins Frailty Score (HFS).

次要结局

  • Length of stay based on a Hopkins Frailty Score (HFS).(30 days)
  • Number of patients Discharge to a skilled or assisted-living facility(30 days)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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