Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 265
- 试验地点
- 1
- 主要终点
- Number of patients with a Complication risk
研究概览
简要总结
Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.
详细描述
Preoperative risk assessment is important, but inexact, in older patients because physiologic reserves are difficult to measure. This also makes an important difference related to brain tumor patients, who may be burdened with systemic disease, alterations in cognition, or affected by other comorbidities. When assessing quality of life for brain tumor patients, having a better predictor of postsurgical outcome would be beneficial in appropriately counseling these patients. Frailty is thought to estimate physiologic reserves, and its use has been found to predict postoperative complications, length of stay, and discharge to a skilled or assisted-living facility in neurosurgical patients. Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current perioperative risk models.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ambulatory (able to walk)
- •Scheduled for neurosurgical resection of brain tumor
排除标准
- •Parkinson disease
- •Previous stroke
- •Taking: carbidopa/levodopa, donepezil hydrochloride, or antidepressants
结局指标
主要结局
Number of patients with a Complication risk
时间窗: 30 days
Number of patients with a complication risk based on a Hopkins Frailty Score (HFS).
次要结局
- Length of stay based on a Hopkins Frailty Score (HFS).(30 days)
- Number of patients Discharge to a skilled or assisted-living facility(30 days)
