Piroxicam and Post-isometric Exercises in Improving Knee Osteoarthritis
Phase 1
Recruiting
- Conditions
- Knee Osteoarthritis with grade 1, 2 and 3.Osteoarthritis of knee
- Registration Number
- IRCT20230202057310N4
- Lead Sponsor
- Muhammad Institute of Medical and Allied Sciences, Multan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
Bilateral knee osteoarthritis (OA) with grade 1,2 and 3
Age 40-75 years
Both genders (male and female)
Cartilage degeneration
Local biomechanical factors (e.g., obesity, joint deformity, muscle weakness)
Nutritional factors
Postmenopausal women
Exclusion Criteria
Neurological disorders (e.g., Alzheimer’s disease, Parkinson’s disease)
Rheumatoid arthritis
Knee replacement patients
Steroidal injection in the past 2 months
Neuropathy
Tumor Knee fractures
Knee osteoarthritis (OA) with grade 4
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain reduction. Timepoint: 12 weeks. Method of measurement: Numeric Pain Rating Scale (NPRS), The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC scale) and pain catastrophizing scale.;Increase in functional ability. Timepoint: 12 weeks. Method of measurement: WOMAC scale.;Swelling reduction. Timepoint: 12 weeks. Method of measurement: Lab investigations.
- Secondary Outcome Measures
Name Time Method Range of motion. Timepoint: 12 weeks. Method of measurement: Goniometry will be used.