Prediction and validation of unipolar depression with psychosocial-somatic markers in a naturalistic cohort recruited in an outpatient setting

Not Applicable

Recruiting

• Conditions: F32; F33; Depressive episode; Recurrent depressive disorder

• Registration Number: DRKS00030203
• Lead Sponsor: Klinik und Poliklinik für Psychiatrie und Psychotherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 950

Inclusion Criteria

Sufficient ability to speak and understand the German language
Female and male subjects between 18-70 years of age
Ability to understand and sign informed consent form
(PHQ>8) - if depressed

Exclusion Criteria

Cognitive impairment that interferes with reliable completion of questionnaires or answering questions.
Presence of manic episode, bipolar disorder, schizophreniform disorders, active eating disorder, active drug or alcohol dependence syndrome
Presence of uncontrolled systemic disease, uncontrolled somatic (other than metabolic or cardiovascular) / neurologic disease, current or recent (last month) physical trauma
Patients with acute suicidal tendencies
Known deficiency of alpha-1 antitrypsin.
Pregnant or lactating women.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PHQ-9, MADRS, GAF after four weeks.

Secondary Outcome Measures

Name	Time	Method
change of body weight, inflammation