E-Freeze: Freezing of embryos in assisted conceptio

Not Applicable

Completed

• Conditions: Infertility; Pregnancy and Childbirth

• Registration Number: ISRCTN61225414
• Lead Sponsor: HS Grampian

Brief Summary

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31196113 (added 17/06/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/34999830/ (added 10/01/2022) 2022 Funder report results in https://pubmed.ncbi.nlm.nih.gov/35603917/ (added 24/05/2022) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39055488/ (added 29/07/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2015-12-29
• Study Completion: 2021-01-31
• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 619

Inclusion Criteria

Current participant inclusion criteria (as of 24/01/2018):
1. The female partner is between 18 and 42 years of age at the start of treatment (i.e. start of ovarian stimulation)
2. Couples who are undergoing their first second or third cycle of IVF/ICSI treatment
3. Both partners are resident in the UK
4. Both partners are able to provide written informed consent

Previous participant inclusion criteria
1. The female partner is between 18 and 42 years of age at the start of treatment (i.e. start of ovarian stimulation)
2. Couples who are undergoing their first cycle of IVF/ICSI treatment
3. Both partners are resident in the UK
4. Both partners are able to provide written informed consent

Exclusion Criteria

Couples in whom:
1. Donor gametes are used
2. Pre-implantation genetic diagnosis is performed
3. Elective freezing of all embryos is preferred or clinically indicated (e.g. severe risk of OHSS)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Health of the baby is determined by medical staff at the time of birth.