To assess tear film changes after intense pulse light therapy in Iranian patients with meibomian gland dysfunction.
Not Applicable
Recruiting
- Conditions
- Meibomian gland dysfunction.Evaporative dry eye- dry eye syndromeH04.1
- Registration Number
- IRCT20190507043503N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Patients with a diagnosis of meibomian gland dysfunction according to international diagnostic criteria
Patients who have ethical consent for participating in the study
Patients who have the history of at least 2 months taking current medications for meibomian gland dysfunction.
Exclusion Criteria
Having any ocular or systemic disease
Having any history of ophthalmic surgeries
Taking medications with photo sensitivity side effects
Contact lens wearers
Having nevus or tattoos in palpebral and peri orbital region
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method OSDI score: this ocular surface index questionnaire consists of 12 question and assesses the severity of dry eye. Timepoint: Baseline, day 14, day 45, day 75. Method of measurement: sum of score of questionnaire which has been filled by the patients.;TBUT : tear break up time. Timepoint: Baseline, day 14, day 45, day 75. Method of measurement: keratograph, slit lamp.;Osmolarity: tear film density. Timepoint: baseline, day 75. Method of measurement: tear lab device.
- Secondary Outcome Measures
Name Time Method Meibomian gland drop out which is graded from 0 to 3. Timepoint: baseline, day 14, day 45, day 75. Method of measurement: keratograph device.;PSQI: Pittsburgh sleep quality index. Timepoint: BASELINE, DAY 75. Method of measurement: Sum of score of questionnaire which has been filed by the patients.