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Comparison of Perioperative Outcomes Between Energy Device During Laparoscopic Gastrectomy

Not Applicable
Completed
Conditions
Postoperative Inflammation
Postoperative Fever
Registration Number
NCT03356626
Lead Sponsor
Seoul National University Hospital
Brief Summary

To find out which instrument can be much better for laparoscopic gastrectomy among Harmonic scalpel, Ligasure Maryland, Thunderbeat

comparing postoperative CRP level in each group

Detailed Description

To find out which instrument can be much better for laparoscopic gastrectomy among Harmonic scalpel, Ligasure Maryland, Thunderbeat

comparing postoperative CRP level in each group

1. post operative 2nd day CRP level

2. post operative 4th day CRP level

3. post operative IL-6, 10 level in 2nd, 4th day

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
189
Inclusion Criteria
  • pathologically proven adenocarcinoma in stomach
  • patients who are expected for R0 resection with distal gastrectomy
  • pre-operative clinical stage should be stage I
  • patients who is able to be followed up with in postoperative 30 days
  • patients whose CRP is normal before surgery
Exclusion Criteria
  • patients who had an abdominal surgery
  • patients who received chemotherapy, radiotherapy before surgery
  • patients who received ESD before surgery
  • Patietns who had an ascites on pre-operative CT scan
  • liver cirrhosis
  • cardiovascular disease (Ejection Fraction<50%)
  • serum creatinine > 1.4 mg/dL or BUN>26mg/dL
  • PT INR >1.2 or aPTT>45sec
  • uncontrolle diabetes
  • Crohn's disease, ulcerative colitis
  • patients who receives anti-coagulants
  • patients who need pre-operative steroid booster because of steroid treatment
  • pregnancy
  • patients who have allergic reaction to iodine

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Postoperative 2nd Day CRP2nd day

To check the postoperative 2nd day CRP level in each group

Secondary Outcome Measures
NameTimeMethod
Postoperative 4th Day CRP4th day

To check the postoperative 4th day CRP level in each group

Postoperative 2nd Day IL-62nd day

To check the postoperative 2nd, 4th day IL-6, IL10 level in each group

Postoperative 4th Day IL-64th day

To check the postoperative 2nd, 4th day IL-6, IL10 level in each group

Postoperative 2nd Day IL-10 Level2nd day

To check the postoperative 2nd, 4th day IL-6, IL10 level in each group

Postoperative 4th Day IL-10 Level4th day

To check the postoperative 2nd, 4th day IL-6, IL10 level in each group

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of

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